PI (3,4) P2is a minor phospholipid component of cell membranes and an important second messenger
PI (3,4) P2is a minor phospholipid component of cell membranes and an important second messenger. Cnt5 from your cytoplasm to cell membranes in response to arsenic stress. These data suggest a model in which Cnt5 contributes to As/Cd resistance by keeping membrane integrity or by modulating membrane trafficking. Keywords:Schizosaccharomyces pombe, cytotoxic stress, weighty metals, cadmium detoxification, arsenic detoxification == Intro == Heavy metals or metalloids such as cadmium (Cd) and arsenic (As) threaten human being health because of their toxicity and persistence in nature. Human exposure is mainly occupational or through environmental contamination such as from toxic waste sites (including numerous Superfund sites), or from naturally contaminated drinking water. The most common oxidation claims of arsenic are +5, +3, and 3. Natural water offers As+3(Arsenite) and As+5(Arsenate) form of As (Fenget al., 2001). Arsenic is known to induce cancers of pores and skin, bladder, liver, kidney, and lung (IARC, 1987;IARC,…