Moreover, one study also suggested the suppression of lung cancer metastasis by concurrently combining hyperthermia and radiotherapy [185]
Moreover, one study also suggested the suppression of lung cancer metastasis by concurrently combining hyperthermia and radiotherapy [185]. and Immunotherapy Radiotherapy is a widely used, well-established anti-tumor treatment that has shown significant clinical outcomes. Utilizing ionizing radiation, radiotherapy generates excessive oxidative stress and induces DNA damage, such as single or double DNA strand breaks, and tumor cell deaths [1]. As radiation can penetrate the body, and can be accurately limited to the depth of interest, AZD2858 radiotherapy is a non-invasive and spatially specific strategy compared to other anti-tumor therapies [2]. However, some tumor cells can be radioresistant, showing resistance to radiation-induced oxidative stress and DNA damage-induced cell death through various intracellular pathways [3,4]. Although increased radiation dose is more likely to induce tumor cell deaths, an excessively high radiation dose can induce damage in adjacent normal tissue and related side effects. For this reason, several radiosensitization strategies have been developed…